Chemistry

Welcome to new group members

Education:
• Ph. D. Chemistry, Indian Institute of Technology (IIT) Guwahati, India, 2010

Professional Experience:

• Assistant Professor: Department of chemistry, University of Louisiana at Monroe, LA. (2016 – Present).
• Graduate Faculty: Department of chemistry, University of Louisiana at Monroe, LA. (2016 – Present).
• Research Scientist: Department of chemistry, University of Louisiana at Lafayette, LA. (2014 – 2016).
• Adjunct Faculty: Department of chemistry, University of Louisiana at Lafayette, LA. (2014 – 2016).
• Postdoctoral Research Scientist: Division of chemistry, Torrey Pines Institute for Molecular Studies, FL. (2012 – 2013).
• Postdoctoral Research Associate: Department of chemistry, University of Louisiana at Lafayette, LA. (2010 – 2012)
• Visiting Scholar: Chemistry division, Institut de Chimie Moléculaire de Reims (ICMR), CNRS - Université de Reims, France. (2008)

Dr. Murru's research is centered on different aspects of synthetic organic chemistry, modern catalysis and medicinal chemistry. His current research involves in the design and development of novel base-metal catalytic systems for the C-C (carbon-carbon) and C-X (carbon-heteroatom) bond forming processes via C-H functionalization. These new catalytic transformations will, in part, be utilized to synthesize N-heterocycles and biologically relevant molecules. The ability to access new types of nitrogen containing molecules can potentially lead to the discovery of new biological entities. The new compounds synthesized in his laboratory will be evaluated for anti-bacterial and anti-cancer activity. Major components of students' training: Students working in his group will gain valuable experience in synthetic experiments, chromatographic separations, instruments handling, data analysis, research philosophy and lab safety.

1. "Fe-catalyzed synthesis of substituted N-aryl oxazolidines" Siva Murru; Charles Seth; Brandon McGough; Dakota Bernard; Radhey S. Srivastava. Org. Biomol. Chem. 2016, 14, 3681.
2. "Iron-catalyzed Direct α C-H Amination of 1,3-Dicarbonyl Compounds and 2-Oxindoles" Siva Murru*; Charles Seth; Radhey S. Srivastava. Org. Lett. 2015, 17, 2122.
3. “Quantum Mechanics Study of Repulsive Π-Π Interaction and Flexibility of Phenyl Moiety in the Iron Azodioxide Complex” Yuemin Liu, Yucheng Liu, Siva Murru, Nianfeng Tzeng, Radhey S. Srivastava. J. Mol. Struct. 2015, 1097, 226.
4. "Synthesis of Substituted Quinolines via Allylic Amination and Intramolecular Heck-Coupling" Siva Murru; Brandon McGough; Radhey S. Srivastava. Org. Biomol. Chem. 2014, 12, 9133.
   (cover-page article:http://pubs.rsc.org/en/content/articlepdf/2014/ob/c4ob90163k
5. "Iron-Catalyzed Allylic C-H Amination of Substituted 1,3-Dienes" Siva Murru; Radhey S. Srivastava. Eur. J. Org. Chem. 2014, 10, 2174.(Highlighted in Organometallic Chemistry News, March 31st 2014)
6. "Combinatorial Synthesis of Oxazol-Thiazole Bis-Heterocyclic Compounds" Siva Murru, Adel Nefzi. ACS Comb. Sci. 2014, 16, 39.
7. "Parallel Synthesis of Bis-Oxazole Peptidomimetics" Siva Murru, Colette Dooley, Adel Nefzi. Tetrahedron Lett. 2013, 54, 7062.
8. "Direct Synthesis of β-alkyl N-Aryl Aza Baylis-Hillman Adducts via Nitroso-Ene Reaction" Siva Murru, August A. Gallo, Radhey S. Srivastava. J. Org. Chem. 2012, 77, 7119.
9. “Ruthenium (II) sulfoxides-catalyzed hydrogenolysis of glycols and epoxides” Siva Murru; Kenneth. M. Nicholas; Radhey S. Srivastava. J. Mol. Cat. A 2012, 363, 460.
10. "Copper-catalyzed Direct Synthesis of 3-Aryl Indoles" Siva Murru, August A. Gallo, Radhey S. Srivastava. Eur. J. Org. Chem. 2011, 11, 2035.
11. "Gold-catalyzed Synthesis of Indoles via Annulation of Nitrosoarenes and Alkynes" Siva Murru, August A. Gallo, Radhey Srivastava. ACS Catal. 2011, 1, 29.
12. “Arylthioureas with Bromine or its Equivalents gives no Hugerschoff Reactions” Ramesh Yella, Siva Murru, Bhisma K. Patel. Org. Biomol. Chem. 2010, 8, 3389.
13. “Efficient Preparation of Isothiocyanates From Dithiocarbamates Using Bromineless Brominating Reagent” Ramesh Yella, Harisadan Ghosh, Siva Murru, Bhisma K. Patel. Synth. Commun. 2010, 40, 2083.
14. “Intra and Intermolecular C-S Bond Formation Using a Single Catalytic System: First Direct Access to Arylthiobenzothiazoles” Siva Murru, Harisadan Ghosh, Santosh K. Sahoo, Bhisma K. Patel. Org. Lett. 2009, 11, 4254. (Highlighted in Synfacts 2009, 12, 1333)
15. “Acylisothiocyanates as Efficient Thiocyanate Transfer Reagents” Charuta C. Palsuledesai; Siva Murru; Santosh K. Sahoo; Bhisma K. Patel. Org. Lett. 2009, 11, 3382.
16. “Copper (I)-Catalyzed Cascade Synthesis of 2-Substituted Benzothiazoles: An Easy Access to Benzothiazolones” Siva Murru, Pravat Mondal, Ramesh Yella, Bhisma K. Patel. Eur. J. Org. Chem. 2009, 31, 5406. (Highlighted in ChemInform 2010; DOI: 10.1002/chin.201007111)
17. “A Comprehensive Decomposition Analysis of Stabilization Energy (CDASE) and its Application in Locating the Rate-determining Step of Multi-step Reactions” Priyanka Bagariya; Soumen Saha; Siva Murru; Veerababurao Kavala; Bhisma K. Patel; Ram Kinkor Roy. Phys. Chem. Chem. Phys. 2009, 11, 8306.
18. “Copper(I)-Catalyzed Synthesis of Substituted 2-Mercapto Benzimidazoles” Siva Murru; Bhisma K. Patel; Jean Le Bras; Jacques Muzart. J. Org. Chem. 2009, 74, 2217.
19. “Hypervalent Iodine(III) Mediated Regioselective N-Acylation of 1,3-Disubstituted Thioureas” C. B. Singh; Harisadan Ghosh; Siva Murru; Bhisma K. Patel. J. Org. Chem. 2008, 73, 2924.
20. “Synthesis and Regiochemistry of enol addition to 9-Phenyl-9H-xanthen-9-ol” Veerababurao Kavala; Siva Murru; Gopal Das; Bhisma K. Patel. Tetrahedron 2008, 64, 3960. (Highlighted in ChemInform 2008; DOI: 10.1002/chin.200836128)
21. “A New Facile Synthetic Method for the Construction of 1,3-Oxathiolane-2-ylidenes” Harisadan Ghosh, Siva Murru; C. B. Singh; Veerababurao Kavala; Bhisma K. Patel. Tetrahedron Lett. 2008, 49, 2601.
22. “A Convenient One-pot Synthesis of Thiazole-2-imines: Application to the Construction of Pifithrin-&alpha Analogues” Siva Murru; C. B. Singh; Veerababurao Kavala; Bhisma K. Patel. Tetrahedron 2008, 64, 1931.
23. “Self-assembled Superstructure of Xanthene Derivatives” Veerababurao Kavala; Siva Murru; Gopal Das; Bhisma K. Patel. J. Chem. Crystallogr. 2007, 37, 527.
24. “3-Aryl-1-benzoylthioureas with alpha-bromoketones in Water form 2-N-Benzoyl-3-arylthiazol-2(3H)-imines, not 3-Aryl-1-benzoylimidazoline-2-thiones” C. B. Singh; Siva Murru; Veerababurao Kavala; Bhisma K. Patel. J. Chem. Res. 2007, 3, 136.
25. “A One-pot Synthesis of 1,4-Dithiins and 1,4-Benzodithiins from Ketones using Recyclable Reagent 1,1’-(Ethane-1,2-diyl) dipyridinium bistribromide (EDPBT)” Siva Murru; Veerababurao Kavala; C. B. Singh; Bhisma K. Patel. Tetrahedron Lett. 2007, 48, 1007. (Highlighted in ChemInform 2007; DOI: 10.1002/chin.200720140)
26. “It is Thiazolylidene and not Imidazole-2-thione as the Reaction Product of 1-Benzoyl-3- phenylthiourea with Br2 / Acetone” C. B. Singh; Siva Murru; Veerababurao Kavala; Bhisma K. Patel. Org. Lett. 2006, 8, 5397.